Endocrine Abstracts

Introduction: Hyponatremia is one of the possible complications of pituitary surgery. Mild, asymptomatic hyponatremia can be managed with fluid restriction and oral supplementation, however more profound hyponatremia, especially when symptomatic, can be a reason for hospital readmission and often needs to be treated with saline infusion in ICU.Aims: To estimate prevalence of hyponatremia and provide clinical characteristics in the cohort of patients who ...

Giant prolactinomas (GPs) are prolactin secreting pituitary adenomas (PitNETs) ≥4 cm, usually with prolactinaemia over 1000 mg/l and without co-secretion of other hormones. Aims: evaluation of long term treatment of GPs, the effect of D2 agonists and of different doses on prolactinaemia, tumour shrinkage and complications.Patients and methods: 33 patients (27 males, 82%) diagnosed with GP in our department between 1997 - 2020...